1643. Pharmacodynamics (PD) of Daptomycin (DAP) in Combination Therapy for Enterococcal Bloodstream Infection (BSI)

Retrospective Study of Linezolid vs. Daptomycin for the Treatment of Vancomycin--resistant Enterococcal Bloodstream Infection

Failure of combination therapy with daptomycin and synergistic ceftriaxone for enterococcal endocarditis.

Department of Pharmacy, Island Health, 1952 Bay St, Victoria, BC V8R 1J8, Canada; Department of Laboratory Medicine, Medical Microbiology Division, Island Health, 1952 Bay St, Victoria, BC V8R 1J8, Canada; Department of Pathology and Laboratory Medicine, University of British Columbia, G227–2211 Wesbrook Mall, Vancouver, BC V6T 2B5, Canada; Department of Infectious Diseases, Island Health, 1952...

Mortality in enterococcal bloodstream infections increases with inappropriate antimicrobial therapy.

Enterococcus species are common in nosocomial bloodstream infections and their incidence is rising. Although well recognized in several serious bacterial infections, the influence of appropriate antimicrobial therapy in enterococcal bacteraemia has not been fully settled. The aim of the study was to determine whether administration of inappropriate antibiotics in enterococcal bacteraemia is an ...

Combination Vancomycin/Cefazolin (VAN/CFZ) for Methicillin-Resistant Staphylococcus aureus (MRSA) Bloodstream Infections (BSI)

777. Combination Vancomycin/Cefazolin (VAN/CFZ) for Methicillin-Resistant Staphylococcus aureus (MRSA) Bloodstream Infections (BSI) Trang D. Trinh, Pharm.D.; Evan J. Zasowski, PharmD, BCPS; Abdalhamid M. Lagnf, M.P.H.; Sahil Bhatia, B.S.; Sorabh Dhar, MD; Ryan Mynatt, PharmD; Jason M. Pogue, PharmD and Michael J. Rybak, PharmD, MPH, PhD; Anti-Infective Research Laboratory, Department of Pharmac...

Genomic Pathways Associated with Daptomycin (DAP) Resistance in DAP-Susceptible Enterococcus faecium Harboring Substitutions in LiaFSR